The most common and most likely answer to this crossword clue is the 5 letter word ROUTE
R
O
U
T
E
More clues leading to the result ROUTE
- After defeat, evil leader gives way
- Convincingly defeat on English course
- Way to completely defeat English
- Course available in religious studies
- Exam subject covering published course
- After heavy defeat English leader shows the way
- Broadcast foundation course
- Course, no longer popular, in RE
- Reportedly, what’s found beneath a trunk road
- Concerning about impossible flight path
Buddy explains!

The straight part
We know that "course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case course = route.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ROUTE mean?
ROUTE noun- A course or way which is traveled or passed.
- A regular itinerary of stops, or the path followed between these stops, such as for delivery or passenger transportation.
- A road or path; often specifically a highway.
- One of multiple methods or approaches to doing something.
- One of the major provinces of imperial China from the Later Jin to the Song, corresponding to the Tang and early Yuan circuits.
- A specific entry in a router that tells the router how to transmit the data it receives.
- To direct or divert along a particular course.
- To connect two local area networks, thereby forming an internet.
- To send (information) through a router.
- To grow roots; to enter the earth, as roots; to take root and begin to grow.
- To prepare, oversee, or otherwise cause the rooting of cuttings
- To be firmly fixed; to be established.
- To get root or priviledged access on a computer system or mobile phone, often through bypassing some security mechanism.
- To turn up or dig with the snout.
- (by extension) To seek favour or advancement by low arts or grovelling servility; to fawn.
- To rummage; to search as if by digging in soil.
- To root out; to abolish.
- To have sexual intercourse.
- (with "for" or "on") To cheer (on); to show support (for) and hope for the success of. (See root for.)