The most common and most likely answer to this crossword clue is the 7 letter word TWOSOME
I've seen this crossword clue in The Guardian
T
W
O
S
O
M
E
More clues leading to the result TWOSOME
- Couple with other siblings, initially in book
- Book about setting up of broadcast item, possibly
- Pair upset by most woe
- Couple in book holding pig back
- Couple getting book about revolutionary seed
- A couple of people owe most, unfortunately
- Couple suffering most woe
- Pair of moody teenagers with pained expression: time to get up
- Climbing plant collected by book group that’s very small
- A couple suffers most woe
Buddy explains!

The straight part
We know that "Couple" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case couple = twosome.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TWOSOME mean?
TWOSOME noun- A group of two; a pair; a couple; a group of two distinct individuals or components.
- A dance for two people.
- Being or constituting a pair; two.
- Twofold; double.
- Performed by two individuals.