Cryptic crossword clue
Couples with destinies altered by sex-change 5

The most common and most likely answer to this crossword clue is the 5 letter word MATES

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Buddy explains!

The straight part

We know that "Couples with" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case couples with = mates.

The cryptic/wordplay part

In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MATES mean?

1. The conclusive victory in a game of chess that occurs when an opponent's king is threatened with unavoidable capture.
2. (by extension) Any losing situation with no escape; utter defeat.

1. To put the king of an opponent into checkmate.
2. (by extension) To place in a losing situation that has no escape.

1. A fellow, comrade, colleague, partner or someone with whom something is shared, e.g. shipmate, classmate.
2. (especially of a non-human animal) A breeding partner.
3. A friend, usually of the same sex.
4. Friendly term of address to a stranger, usually male, of similar age
5. In naval ranks, a non-commissioned officer or his subordinate (e.g. Boatswain's Mate, Gunner's Mate, Sailmaker's Mate, etc).
6. A ship's officer, subordinate to the master on a commercial ship.
7. A first mate.
8. A technical assistant in certain trades (e.g. gasfitter's mate, plumber's mate); sometimes an apprentice.
9. The other member of a matched pair of objects.
10. A suitable companion; a match; an equal.

1. To match, fit together without space between.
2. To copulate.
3. To pair in order to raise offspring
4. To arrange in matched pairs.
5. To introduce (animals) together for the purpose of breeding.
6. (of an animal) To copulate with.
7. To marry; to match (a person).
8. To match oneself against; to oppose as equal; to compete with.
9. To fit (objects) together without space between.
10. To move (a space shuttle orbiter) onto the back of an aircraft that can carry it.

1. To confuse; to confound.

1. The abovementioned plant; the leaves and shoots used for the tea

1. Friendly; having a friendship (with).

1. An evergreen tree, Ilex paraquariensis, native to South America, cultivated for its leaves.
2. A beverage, resembling tea, made from the dried leaves of this plant.
3. A cup of this drink.

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