The most common and most likely answer to this crossword clue is the 6 letter word ENTREE
I've seen this crossword clue in Independent
E
N
T
R
E
E
More clues leading to the result ENTREE
- Unqualified, one abandons English course
- Menu item’s recent re-emergence, somewhat reduced
- Course finally eaten in Eastern plane, perhaps?
- Course of rare drugs started by hospital department
- Starter for ten about the beginnings of Russia’s eastern expansion
- Dish made from bent reeds
- Dish carried by salver, as the English say
- English conservationists note European introduction
- …course there’s space on plane for one
- Admission granted for course
Buddy explains!

The straight part
We know that "Course" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case course = entree.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ENTREE mean?
ENTREE noun- (French Canada) A smaller dish served before the main course of a meal.
- The main course or main dish of a meal.
- The act of entering somewhere, or permission to enter; admittance.
- An introduction or prelude.