Cryptic crossword clue
Cream puff made with a staple grain from the east has the French filling 6

The most common and most likely answer to this crossword clue is the 6 letter word ECLAIR

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Buddy explains!

The straight part
We know that "Cream puff" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cream puff = eclair.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ECLAIR mean?

ECLAIR noun
  1. An oblong, chocolate-covered, cream-filled pastry.

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