Cryptic crossword clue
Create stress as cut announced by hospital dept posh dislike in the East End 10

The most common and most likely answer to this crossword clue is the 10 letter word ACCENTUATE

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Buddy explains!

The straight part
We know that "Create stress" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case create stress = accentuate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ACCENTUATE mean?

ACCENTUATE verb
  1. To pronounce with an accent or vocal stress.
  2. To bring out distinctly; to make more noticeable or prominent; to emphasize.
  3. To mark with a written accent.

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