The most common and most likely answer to this crossword clue is the 7 letter word TOILETS
I've seen this crossword clue in The Sunday Telegraph
T
O
I
L
E
T
S
More clues leading to the result TOILETS
Buddy explains!

The straight part
We know that "ladies and gentlemen" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case ladies and gentlemen = toilets.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does TOILETS mean?
TOILETS noun- A covering of linen, silk, or tapestry, spread over a dressing table in a chamber or dressing room.
- The table covered by such a cloth; a dressing table.
- Personal grooming; the process of washing, dressing and arranging the hair.
- One's style of dressing: dress, outfit.
- A dressing room.
- A room or enclosed area containing a toilet: a bathroom or water closet.
- A small secondary lavatory having a toilet and sink but no bathtub or shower.
- A chamber pot.
- A fixture used for urination and defecation, particularly those with a large bowl and ring-shaped seat which use water to flush the waste material into a septic tank or sewer system.
- A very shabby or dirty place.
- To dress and groom oneself
- To use the toilet
- To assist another (a child etc.) in using the toilet