The most common and most likely answer to this crossword clue is the 6 letter word WHOOPS
I've seen this crossword clue in Independent
W
H
O
O
P
S
More clues leading to the result WHOOPS
- Doctor overlooking procedures? Oh dear!
- . Cries when wife rings?
- Doctor works and cries at mistake
- Cries “I’ve made a mistake!”
- Cheers, I didn’t mean to do that
- Auden, oh dear, oh dear!
- Accepting work, that’s my mistake
- Alarming exclamation from TV doctor before surgical procedures!
- It’s heard after a mistake with rings
- Exclamation of mistake from doctor attending surgical procedures
Buddy explains!

The straight part
We know that "Cries/“I’ve made a mistake!”" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cries/“i’ve made a mistake!” = whoops.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WHOOPS mean?
WHOOPS interjection- Oops.
- A loud, eager cry, usually of joy.
- A gasp, characteristic of whooping cough.
- A bump on a racetrack.
- To make a whoop.
- To shout, to yell.
- To cough or breathe with a sonorous inspiration, as in whooping cough.
- To insult with shouts; to chase with derision.
- To beat, to strike.
- To defeat thoroughly.