Cryptic crossword clue
Cruel destiny imprisoning the first-born 6

The most common and most likely answer to this crossword clue is the 6 letter word ELDEST

I've seen this crossword clue in The Daily Telegraph
E
L
D
E
S
T


Buddy explains!

The straight part
We know that "the first-born" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case the first-born = eldest.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ELDEST mean?

ELDEST noun
  1. The eldest child in a family, or individual in a group.
ELDEST adjective
  1. (of a player) Receiving cards from the dealer first, before any other players.
  2. (of a hand) Having higher, or superior cards.
ELDEST adjective
  1. Of an object, concept, relationship, etc., having existed for a relatively long period of time.
  2. Having been used and thus no longer new or unused.
  3. Having existed or lived for the specified time.
  4. (heading) Of an earlier time.
  5. Tiresome after prolonged repetition.
  6. Said of subdued colors, particularly reds, pinks and oranges, as if they had faded over time.
  7. A grammatical intensifier, often used in describing something positive. (Mostly in idioms like good old, big old and little old, any old and some old.)
  8. Excessive, abundant.

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