Cryptic crossword clue
Cultured and calm, holding small cleaning item I flog 12

The most common and most likely answer to this crossword clue is the 12 letter word COSMOPOLITAN

I've seen this crossword clue in The Daily Telegraph
C
O
S
M
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P
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A
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Buddy explains!

The straight part
We know that "Cultured" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cultured = cosmopolitan.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COSMOPOLITAN mean?

COSMOPOLITAN noun
  1. A cosmopolitan person; a cosmopolite.
  2. A cocktail containing vodka, triple sec, lime juice and cranberry juice.
  3. A butterfly, Vanessa cardui
COSMOPOLITAN adjective
  1. Inclusive; affecting the whole world.
  2. (of a place or institution) composed of people from all over the world.
  3. (of a person) at ease in any part of the world; familiar with many cultures.
  4. Growing or living in many parts of the world; widely distributed.

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