The most common and most likely answer to this crossword clue is the 6 letter word JUICED
I've seen this crossword clue in Independent
J
U
I
C
E
D
Buddy explains!
The straight part
We know that "drunk in America" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drunk in america = juiced.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does JUICED mean?
JUICED verb- To extract the juice from something.
- To energize or stimulate something.
- (of a fruit etc) That has had the juice extracted.
- Drunk.
- Excited.
- On steroids.