The most common and most likely answer to this crossword clue is the 10 letter word BLINDFOLDS
I've seen this crossword clue in The Times
B
L
I
N
D
F
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L
D
S
More clues leading to the result BLINDFOLDS
Buddy explains!
The straight part
We know that "lack of vision with these" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lack of vision with these = blindfolds.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BLINDFOLDS mean?
BLINDFOLDS noun- A covering, usually a bandage, for the eyes, blocking light to the eyes.
- Something that obscures vision (literally or metaphorically).
- To cover the eyes, in order to make someone unable to see.
- To obscure understanding or comprehension.