The most common and most likely answer to this crossword clue is the 10 letter word BLASPHEMED
I've seen this crossword clue in The Times
B
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Buddy explains!

The straight part
We know that "Cursed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case cursed = blasphemed.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BLASPHEMED mean?
BLASPHEMED verb- To commit blasphemy; to speak against God or religious doctrine.
- To speak of, or address, with impious irreverence; to revile impiously (anything sacred).
- To calumniate; to revile; to abuse.