Cryptic crossword clue
Cuts off and, also, ties off 8

The most common and most likely answer to this crossword clue is the 8 letter word ISOLATES

I've seen this crossword clue in The Guardian
I
S
O
L
A
T
E
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does ISOLATES mean?

ISOLATES noun
  1. Something that has been isolated.
ISOLATES verb
  1. To set apart or cut off from others.
  2. To place in quarantine or isolation.
  3. To separate a substance in pure form from a mixture.
  4. To insulate, or make free of external influence.
  5. To separate a pure strain of bacteria etc. from a mixed culture.
  6. To insulate an electrical component from a source of electricity.

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