Cryptic crossword clue
Daughter, say, with pimples, about to be confined to a room 7

The most common and most likely answer to this crossword clue is the 7 letter word ENCAGED

E
N
C
A
G
E
D

Buddy explains!

The straight part
We know that "confined to a room" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case confined to a room = encaged.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ENCAGED mean?

ENCAGED verb
  1. To lock inside a cage; to imprison.

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