Cryptic crossword clue
De Niro part almost recast for ‘Doom‘ 9

The most common and most likely answer to this crossword clue is the 9 letter word PREORDAIN

I've seen this crossword clue in The Daily Telegraph
P
R
E
O
R
D
A
I
N

Buddy explains!

The straight part
We know that "Doom" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case doom = preordain.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PREORDAIN mean?

PREORDAIN verb
  1. To determine the fate of something in advance.

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