Cryptic crossword clue
Defeated and heart-broken, the lady would lose hope in the end 8

The most common and most likely answer to this crossword clue is the 8 letter word THRASHED

T
H
R
A
S
H
E
D

Buddy explains!

The straight part
We know that "Defeated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case defeated = thrashed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does THRASHED mean?

THRASHED verb
  1. To beat mercilessly.
  2. To defeat utterly.
  3. To thresh.
  4. To move about wildly or violently; to flail; to labour.
  5. To extensively test a software system, giving a program various inputs and observing the behavior and outputs that result.
  6. In computer architecture, to cause poor performance of a virtual memory (or paging) system.

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