The most common and most likely answer to this crossword clue is the 6 plus 9 letter word BUNKER MENTALITY
I've seen this crossword clue in Independent
B
U
N
K
E
R
M
E
N
T
A
L
I
T
Y
Buddy explains!

The straight part
We know that "Defensive paranoia" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case defensive paranoia = bunker mentality.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.