Cryptic crossword clue
Demand something from vain sister 6

The most common and most likely answer to this crossword clue is the 6 letter word INSIST

I
N
S
I
S
T


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The straight part
We know that "Demand" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case demand = insist.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INSIST mean?

INSIST verb
  1. (with on or upon or (that + ordinary verb form)) To hold up a claim emphatically.
  2. (sometimes with on or upon or (that + subjunctive)) To demand continually that something happen or be done.
  3. To stand (on); to rest (upon); to lean (upon).

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