Cryptic crossword clue
Depressing quality of extremely deplorable town not Stoke

The most common and most likely answer to this crossword clue is the 8 letter word DEBASING

I've seen this crossword clue in The Guardian
D
E
B
A
S
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G

Buddy explains!

The straight part
We know that "Depressing" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case depressing = debasing.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DEBASING mean?

DEBASING verb
  1. To lower in character, quality, or value; to degrade.
  2. To lower in position or rank.
  3. To lower the value of (a currency) by reducing the amount of valuable metal in the coins.

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