The most common and most likely answer to this crossword clue is the 7 letter word BLINDED
I've seen this crossword clue in The Guardian
B
L
I
N
D
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D
More clues leading to the result BLINDED
Buddy explains!

The straight part
We know that "Deprived of sense" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case deprived of sense = blinded.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BLINDED mean?
BLINDED verb- To make temporarily or permanently blind.
- To curse.
- To darken; to obscure to the eye or understanding; to conceal.
- To cover with a thin coating of sand and fine gravel, for example a road newly paved, in order that the joints between the stones may be filled.
- Deprived of sight.
- Lacking intellectual discernment, for example because of greed or stupidity.
- Covered by blinds.
- (of a bus) Displaying a particular destination or route number on the blinds.