The most common and most likely answer to this crossword clue is the 6 letter word PINEAL
P
I
N
E
A
L
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does PINEAL mean?
PINEAL noun- The pineal gland.
- In the shape of a pine cone.
- Pertaining to the pineal gland.