Cryptic crossword clue
Design single duct to carry nitrogen 6

The most common and most likely answer to this crossword clue is the 6 letter word INVENT

I've seen this crossword clue in The Daily Telegraph
I
N
V
E
N
T

Buddy explains!

The straight part
We know that "Design" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case design = invent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INVENT mean?

INVENT verb
  1. To design a new process or mechanism.
  2. To create something fictional for a particular purpose.
  3. To come upon; to find; to discover.

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