Cryptic crossword clue
Desperately stir acidic bits of crème fraîche? 10

The most common and most likely answer to this crossword clue is the 10 letter word DIACRITICS

I've seen this crossword clue in Independent
D
I
A
C
R
I
T
I
C
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DIACRITICS mean?

DIACRITICS noun
  1. A special mark added to a letter to indicate a different pronunciation, stress, tone, or meaning.

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