The most common and most likely answer to this crossword clue is the 5 letter word BOUND
I've seen this crossword clue in The Times
B
O
U
N
D
Buddy explains!

The straight part
We know that "Destined/leap" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case destined/leap = bound.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does BOUND mean?
BOUND verb- To tie; to confine by any ligature.
- To cohere or stick together in a mass.
- To be restrained from motion, or from customary or natural action, as by friction.
- To exert a binding or restraining influence.
- To tie or fasten tightly together, with a cord, band, ligature, chain, etc.
- To confine, restrain, or hold by physical force or influence of any kind.
- To couple.
- To oblige, restrain, or hold, by authority, law, duty, promise, vow, affection, or other social tie.
- To put (a person) under definite legal obligations, especially, under the obligation of a bond or covenant.
- To place under legal obligation to serve.
- To protect or strengthen by applying a band or binding, as the edge of a carpet or garment.
- To make fast (a thing) about or upon something, as by tying; to encircle with something.
- To cover, as with a bandage.
- To prevent or restrain from customary or natural action, as by producing constipation.
- To put together in a cover, as of books.
- To make two or more elements stick together.
- To associate an identifier with a value; to associate a variable name, method name, etc. with the content of a storage location.
- To complain; to whine about something.
- (with infinitive) Obliged (to).
- (of a morpheme) That cannot stand alone as a free word.
- (of a variable) Constrained by a quantifier.
- Constipated; costive.
- Confined or restricted to a certain place; e.g. railbound.
- Unable to move in certain conditions; e.g. snowbound.
- Ready, prepared.
- Ready to start or go (to); moving in the direction (of).
- (with infinitive) Very likely (to), certain to
- (often used in plural) A boundary, the border which one must cross in order to enter or leave a territory.
- A value which is known to be greater or smaller than a given set of values.
- To surround a territory or other geographical entity.
- To be the boundary of.
- A sizeable jump, great leap.
- A spring from one foot to the other in dancing.
- A bounce; a rebound.
- To leap, move by jumping.
- To cause to leap.
- To rebound; to bounce.
- To cause to rebound; to throw so that it will rebound; to bounce.