Cryptic crossword clue
Destroys trains after odd Earl leaves 7

The most common and most likely answer to this crossword clue is the 7 letter word EXCISES

E
X
C
I
S
E
S

Buddy explains!

The straight part
We know that "Destroys" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case destroys = excises.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXCISES mean?

EXCISES noun
  1. A tax charged on goods produced within the country (as opposed to customs duties, charged on goods from outside the country).

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