Cryptic crossword clue
Details of run-in for mediator lacking awareness 10

The most common and most likely answer to this crossword clue is the 10 letter word UNINFORMED

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Buddy explains!

The straight part
We know that "lacking awareness" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case lacking awareness = uninformed.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNINFORMED mean?

UNINFORMED adjective
  1. Not informed; ignorant.
  2. Not imbued with life or activity.

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