Cryptic crossword clue
Detect man in NHS wanting reform, being fed up 14

The most common and most likely answer to this crossword clue is the 14 letter word DISENCHANTMENT

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "being fed up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case being fed up = disenchantment.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISENCHANTMENT mean?

DISENCHANTMENT noun
  1. The act of disenchanting or the state of being disenchanted.
  2. Freeing from false belief or illusions.

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