Cryptic crossword clue
Detrimental, hard, and as much as one can bear 7

The most common and most likely answer to this crossword clue is the 7 letter word HARMFUL

I've seen this crossword clue in The Sunday Telegraph
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Buddy explains!

The straight part
We know that "Detrimental" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case detrimental = harmful.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HARMFUL mean?

HARMFUL adjective
  1. Of a kind likely to be damaging; injurious

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