The most common and most likely answer to this crossword clue is the 12 letter word DOMESTICATED
I've seen this crossword clue in The Times
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More clues leading to the result DOMESTICATED
Buddy explains!

The straight part
We know that "no longer wild" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case no longer wild = domesticated.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DOMESTICATED mean?
DOMESTICATED verb- To make domestic.
- To make fit for domestic life.
- To adapt to live with humans.
- To adapt to live with humans.
- To make a legal instrument recognized and enforceable in a jurisdiction foreign to the one in which the instrument was originally issued or created.
- To amend the elements of a text to fit local culture.
- (of an animal or a plant, especially a pet) selectively bred to live with or around humans.