Cryptic crossword clue
Difficult performing? Without this, certainly! 4-2

The most common and most likely answer to this crossword clue is the 7 letter word HARD-ON

H
A
R
D
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O
N

Buddy explains!

The straight part
We know that "without this, (it would) certainly (be difficult to perform, sexually)" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case without this, (it would) certainly (be difficult to perform, sexually) = hard-on.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HARD-ON mean?

HARD-ON noun
  1. An erection of the penis.

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