Cryptic crossword clue
Difficulty produced by aggravation of illness 12

The most common and most likely answer to this crossword clue is the 13 letter word COMPLICATIONS

I've seen this crossword clue in The Daily Telegraph
C
O
M
P
L
I
C
A
T
I
O
N
S

Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COMPLICATIONS mean?

COMPLICATIONS noun
  1. The act or process of complicating.
  2. The state of being complicated; intricate or confused relation of parts; complexity.
  3. A person who doesn't fit in with the main scheme of things; an interloper.
  4. A disease or diseases, or adventitious circumstances or conditions, coexistent with and modifying a primary disease, but not necessarily connected with it.
  5. A feature beyond basic time display in a timepiece.

Latest crossword clues with full explanations