Cryptic crossword clue
Difficulty with knot 5

The most common and most likely answer to this crossword clue is the 5 letter word HITCH

I've seen this crossword clue in Financial Times
H
I
T
C
H

Buddy explains!

The straight part
We know that "Difficulty/knot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case difficulty/knot = hitch.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HITCH mean?

HITCH noun
  1. A sudden pull.
  2. Any of various knots used to attach a rope to an object other than another rope.
  3. A fastener or connection point, as for a trailer.
  4. A problem, delay or source of difficulty.
  5. A hidden or unfavorable condition or element; a catch.
  6. A period of time spent in the military.
HITCH verb
  1. To pull with a jerk.
  2. To attach, tie or fasten.
  3. To marry oneself to; especially to get hitched.
  4. Contraction of hitchhike, to thumb a ride.
  5. To become entangled or caught; to be linked or yoked; to unite; to cling.
  6. To move interruptedly or with halts, jerks, or steps; said of something obstructed or impeded.
  7. To strike the legs together in going, as horses; to interfere.

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