Cryptic crossword clue
Digging out toxin, react poorly 10

The most common and most likely answer to this crossword clue is the 10 letter word EXTRACTION

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Buddy explains!

The straight part
We know that "Digging out" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case digging out = extraction.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EXTRACTION mean?

EXTRACTION noun
  1. An act of extracting or the condition of being extracted.
  2. A person's origin or ancestry.
  3. Something extracted, an extract, as from a plant or an organ of an animal etc.
  4. An act of removing someone from a hostile area to a secure location.
  5. A removal of a tooth from its socket.

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