The most common and most likely answer to this crossword clue is the 6 letter word DANGER
I've seen this crossword clue in The Guardian
D
A
N
G
E
R
More clues leading to the result DANGER
- Risk in badly laid-out garden
- Risk pulling line from hanging item
- Note great annoyance where such hazard is created?
- Knot garden creating hazard
- Dire peril
- . Risk associated ultimately with negative emotion
- Peril in rock garden
- Insecurity makes director fret
- Element of risk in garden design
- Threat of terminal road rage
Buddy explains!

The straight part
We know that "peril" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case peril = danger.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DANGER mean?
DANGER noun- Exposure to likely harm; peril.
- An instance or cause of likely harm.
- Mischief.
- (mainly outside US) The stop indication of a signal (usually in the phrase "at danger").
- Ability to harm; someone's dominion or power to harm or penalise. See in one's danger, below.
- Liability.
- Difficulty; sparingness.
- Coyness; disdainful behavior.
- To claim liability.
- To imperil; to endanger.
- To run the risk.