Cryptic crossword clue
Direct contact process is one in which inert gas combines with oxygen 3-2-3

The most common and most likely answer to this crossword clue is the 10 letter word ONE-ON-ONE

O
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O
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Buddy explains!

The straight part
We know that "Direct contact process" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case direct contact process = one-on-one.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ONE-ON-ONE mean?

ONE-ON-ONE noun
  1. A contest involving only one player on each side, especially of an activity often involving teams.
ONE-ON-ONE adjective
  1. Involving direct communication between two people.
  2. Involving one attacker and one defender
  3. Bijective or injective

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