Cryptic crossword clue
Disability of old man in Machu Picchu, say? 10

The most common and most likely answer to this crossword clue is the 10 letter word INCAPACITY

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Buddy explains!

The straight part
We know that "Disability" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case disability = incapacity.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INCAPACITY mean?

INCAPACITY noun
  1. The lack of a capacity; an inability.
  2. Legal disqualification.

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