Cryptic crossword clue
Disease running rampant in Serbia 6

The most common and most likely answer to this crossword clue is the 6 letter word RABIES

I've seen this crossword clue in The Daily Telegraph
R
A
B
I
E
S

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does RABIES mean?

RABIES noun
  1. An infectious disease caused by species of Lyssavirus that causes acute encephalitis in warm-blooded animals and people, characterised by abnormal behaviour such as biting, excitement, aggressiveness, and dementia, followed by paralysis and death.

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