The most common and most likely answer to this crossword clue is the 10 letter word STROGANOFF
I've seen this crossword clue in The Guardian
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Buddy explains!
The straight part
We know that "Dish of beef" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case dish of beef = stroganoff.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does STROGANOFF mean?
STROGANOFF noun- A dish of sautéed pieces of beef (or a substitute) served in a sauce with sour cream.