Cryptic crossword clue
Disorder resulting from a mishap, a terrible loss of memory primarily 7

The most common and most likely answer to this crossword clue is the 7 letter word APHASIA

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Buddy explains!

The straight part
We know that "Disorder" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case disorder = aphasia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APHASIA mean?

APHASIA noun
  1. A partial or total loss of language skills due to brain damage. Usually, damage to the left perisylvian region, including Broca's area and Wernicke's area, causes aphasia.

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