Cryptic crossword clue
Disorderly males in bus that cannot be overlooked 10

The most common and most likely answer to this crossword clue is the 10 letter word UNMISSABLE

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "that cannot be overlooked" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case that cannot be overlooked = unmissable.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNMISSABLE mean?

UNMISSABLE adjective
  1. Not to be missed; thoroughly worth seeing or experiencing.
  2. Impossible to miss.

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