Cryptic crossword clue
Disoriented artist left redefined Lake District and was defeated 6

The most common and most likely answer to this crossword clue is the 6 letter word LICKED

L
I
C
K
E
D

Buddy explains!

The straight part
We know that "defeated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case defeated = licked.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LICKED mean?

LICKED verb
  1. To stroke with the tongue.
  2. To lap; to take in with the tongue.
  3. To beat with repeated blows.
  4. To defeat decisively, particularly in a fight.
  5. To overcome.
  6. To perform cunnilingus.
  7. To do anything partially.
  8. (of flame, waves etc.) To lap.

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