Cryptic crossword clue
Disturbance from American on vehicle not starting 6

The most common and most likely answer to this crossword clue is the 6 letter word RUCKUS

R
U
C
K
U
S

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The straight part
We know that "Disturbance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case disturbance = ruckus.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RUCKUS mean?

RUCKUS noun
  1. A noisy disturbance and/or commotion.
  2. A row, fight.

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