Cryptic crossword clue
Do not open trashy bottled wine 5

The most common and most likely answer to this crossword clue is the 5 letter word SYRAH

I've seen this crossword clue in Financial Times
S
Y
R
A
H

Buddy explains!

The straight part
We know that "wine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case wine = syrah.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SYRAH mean?

SYRAH noun
  1. A dark-skinned variety of grape, used to produce red wines.
  2. A wine produced from this variety of grape.

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