Cryptic crossword clue
Doctor in North America uses anaesthetic 5

The most common and most likely answer to this crossword clue is the 5 letter word NUMBS

I've seen this crossword clue in The Daily Telegraph
N
U
M
B
S

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The straight part
We know that "uses anaesthetic" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case uses anaesthetic = numbs.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does NUMBS mean?

NUMBS verb
  1. To cause to become numb (physically or emotionally).
  2. To cause (a feeling) to be less intense.
  3. To cause (the mind, faculties, etc.) to be less acute.
  4. To become numb (especially physically).

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