Cryptic crossword clue
Doctor inserted syringe's tip to have softening effect 9

The most common and most likely answer to this crossword clue is the 9 letter word TENDERISE

I've seen this crossword clue in The Times
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Buddy explains!

The straight part
We know that "to have softening effect" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to have softening effect = tenderise.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TENDERISE mean?

TENDERISE verb
  1. To make (something, especially meat) tender.

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