Cryptic crossword clue
Doctor said “All OK No sugar, for starters, and caffeine, maybe” 8

The most common and most likely answer to this crossword clue is the 8 letter word ALKALOID

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Buddy explains!

The straight part
We know that "caffeine, maybe" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case caffeine, maybe = alkaloid.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ALKALOID mean?

ALKALOID noun
  1. Any of many organic heterocyclic bases that occur in nature and often have medicinal properties.
ALKALOID adjective
  1. Relating to, resembling, or containing alkali.

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