The most common and most likely answer to this crossword clue is the 8 letter word YOGHOURT
I've seen this crossword clue in Financial Times
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More clues leading to the result YOGHOURT
Buddy explains!
The straight part
We know that "Does its consumption make one cultured" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case does its consumption make one cultured = yoghourt.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does YOGHOURT mean?
YOGHOURT noun- A milk-based product stiffened by a bacterium-aided curdling process, and sometimes mixed with fruit or other flavoring.
- (especially in compounds) Any similar product based on other substances (e.g. soy yogurt).