Cryptic crossword clue
Doggedness in demanding Cardinal cuts iciness in negotiation 10

The most common and most likely answer to this crossword clue is the 10 letter word INSISTENCE

I
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Buddy explains!

The straight part
We know that "Doggedness in demanding" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case doggedness in demanding = insistence.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INSISTENCE mean?

INSISTENCE noun
  1. The state of being insistent.
  2. An urgent demand.
  3. The forcing of an attack through the parry, using strength.

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