Cryptic crossword clue
Doing well to disperse Lisbon smog 10

The most common and most likely answer to this crossword clue is the 10 letter word BLOSSOMING

I've seen this crossword clue in The Guardian
B
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Buddy explains!

The straight part
We know that "Doing well" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case doing well = blossoming.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BLOSSOMING mean?

BLOSSOMING verb
  1. To have, or open into, blossoms; to bloom.
  2. To begin to thrive or flourish.
BLOSSOMING noun
  1. The act or process by which something blossoms.

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